Writers (I know something about it), editors, graphic designers… the vast majority of work on a PC requires continuous use of the mouse and keyboard. However, while the keyboard mainly causes wrist fatigue, the numbness in the fingers that is felt after prolonged mouse use (even the vertical version, like in the photo above) can eventually lead to serious issues: paresthesias, burning sensations, tingling, or even worse, carpal tunnel syndrome.
If it’s not possible to limit mouse usage or at least take breaks proportional to its duration, it is advisable to at least perform some hand exercises from time to time.
1. 5 minutes of this hand grippers, at least 2 times a day. It also helps make the forearm stronger.

2. Hand stretching — place one finger at a time against the edge of a table, desk, or any other surface that can serve as resistance, and push as far as you can without causing too much pain. Hold each position for at least 30 seconds per finger.

3. Get one (or two) of these hand and wrist rehabilitation balls and use it frequently during work. Squeezing it also works as an anti-stress activity.

It applies to both hands, of course, with particular attention to the one that is used most often or is most fatigued.